How does vitamin D supplementation impact COVID-19 vaccine efficacy?

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of vitamin D supplementation on the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

Study: Influence of vitamin D supplementation on SARS-CoV-2 vaccine efficacy and immunogenicity. Image Credit: Fast Speeds Imagery/Shutterstock

Coronavirus disease 2019 (COVID-19) vaccination has played a critical role in controlling the COVID-19 pandemic. However, studies have reported the waning of vaccine effectiveness and efficacy in the months after vaccination, particularly among elderly individuals. Hence, there is an urgent need to identify immunomodulatory adjuvants that can improve SARS-CoV-2 vaccine immunogenicity.    

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